Research Interest

The Lab and Personnel

Major Honors

Editor and Editorial Board


Positions Available

News Release



Publication lists

  1. Piao X, Yin H, Guo S, Wang H, Guo P. RNA Nanotechnology to Solubilize Hydrophobic Antitumor Drug for Targeted Delivery. Adv. Sci. 2019 Sep;1900951.[link][PDF]
  2. Guo S, Xu C, Yin H, Hill J, Pi F, Guo P. Tuning the size and structure of RNA nanoparticles for favorable cancer targeting and immunostimulation. WIREs Nanomed Nanobiotechnol. 2019 Aug;311-312:43-49.[link][PDF]
  3. Li H, Wang S, Ji Z, Xu C, Shlyakhtenko, Guo P. Construction of RNA nanotubes. Nano Research. 2019 Aug;1952-1958.[link][PDF]
  4. Zheng Z, Li Z, Xu C, Guo B, Guo P. Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping. J Control Release. 2019 Oct;311-312:43-49.[link][PDF]
  5. Ji Z, Guo P. Channel from bacterial virus T7 DNA packaging motor for the differentiation of peptides composed of a mixture of acidic and basic amino acids. Biomaterials. 2019 May 21;214:119222.[link][PDF]
  6. Guo P, Driver D, Zhao Z, Zheng Z, Chan C, Cheng X. Controlling the Revolving and Rotating Motion Direction of Asymmetric Hexameric Nanomotor by Arginine Finger and Channel Chirality. ACS Nano. 2019 May 8;13(6):6207-6223.[link][PDF]
  7. Das S, Extracellular RNA Communication Consortium, et al. The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research. Cell. 2019 Apr 4;177(2):231-242.[link][PDF]
  8. Yin H, Xiong G, Guo S, Xu C, Xu R, Guo P, Shu D. Delivery of Anti-miRNA for Triple Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting to Stem Cell Marker CD133. Molecular Therapy. 2019 Jul 03;27(7):1252-1261.[link][PDF]
  9. Jasinski DL, Binzel DW, Guo P. One-Pot Production of RNA Nanoparticles via Automated Processing and Self-Assembly. ACS Nano. 2019 Apr 23;13(4):4603-4612.[link][PDF]
  10. Yin H, Wang H, Li Z, Shu D, Guo P. RNA Micelles for Systemic Delivery of Anti-miRNA for Cancer Targeting and Inhibition without Ligand. ACS Nano. 2019 Jan 22;13(1):706-717.[link][PDF]
  11. Xu C, Li H, Zhang K, Binzel D, Yin H, Chiu W, Guo P. Photo-controlled release of paclitaxel and model drugs from RNA pyramids. Nano Research. 2019;12: 41.[link][PDF]

  12. 2018
  13. Xu Y, Pang L, Wang H, Xu C, Shah H, Guo P, Shu D, Qian SY. Specific delivery of delta-5-desaturase siRNA via RNA nanoparticles supplemented with dihomo-y-linolenic acid for colon cancer suppression. Redox Biol. 2018 Dec 18;21:101085.[link][PDF]
  14. Li Z, Wang H, Yin H, Bennett C, Zhang H, Guo P. Arrowtail RNA for Ligand Display on Ginger Exosome-like Nanovesicles to Systemic Deliver siRNA for Cancer Suppression. Sci Rep. 2018 Oct 2;8(1):14644.[link][PDF]
  15. Ji Z, Kang X, Wang S, Guo P. Nano-channel of viral DNA packaging motor as single pore to differentiate peptides with single amino acid difference. Biomaterials. 2018 Nov;182:227-233.[link][PDF]
  16. Haque F, Zhang H, Wang S, Chang CL, Savran C, Guo P. Methods for Single-Molecule Sensing and Detection Using Bacteriophage Phi29 DNA Packaging Motor. Methods Mol Biol. 2018;1805:423-450.[link][PDF]
  17. Guo S, Piao X, Li H, Guo P. Methods for Construction and Characterization of Simple or Special Multifunctional RNA Nanoparticles Based on the 3WJ of Phi29 DNA Packaging Motor. Methods. 2018 Jul 1;143:121-133.[link][PDF]
  18. Shu Y, Yin H, Rajabi M, Li H, Vieweger M, Guo S, Shu D, Guo P. RNA-based micelles: A novel platform for paclitaxel loading and delivery. J Control Release. 2018 Feb 14;276:17-29. [link][PDF]
  19. Jasinki D, Li H, Guo P. The Effect of Size and Shape of RNA Nanoparticles on Biodistribution. Molecular Therapy. 2018 Mar 7;26(3):784-792. [link][PDF]
  20. Smith J, Braga A, Verheyen J, Basilico S, Bandiera S, Alfaro-Cervello C, Peruzzotti-Jametti L, Shu D, Haque F, Guo P, and Pluchino S. RNA nanotherapeutics for the amelioration of astroglial reactivity. Mol Ther Nucleic Acids. 2018 Mar; 10:103-121. [link][PDF]
  21. Pi F, Binzel D, Lee TJ, Li Z, Sun M, Rychahou P, Li H, Haque F, Wang S, Croce CM, Guo B, Evers BM,Guo P. Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression. Nature Nanotechnology. 2018 Jan; 13(1):82-89. [link][PDF]
  22. Wang S, Zhao Z, Haque F, Guo P. Engineering of protein nanopores for sequencing, chemical or protein sensing and disease diagnosis. Current Opinion in Biotechnology. 2018 Jun; 51:80-89. [link][PDF]
  23. Haque F, Pi F, Zhao Z, Gu S, Hu H, Yu H, Guo P. RNA versatility, flexibility, and thermostability for practice in RNA nanotechnology and biomedical applications. Wiley Interdiscip Rev RNA. 2018 Jan; 9(1). [link][PDF]
  24. Piao X, Wang H, Binzel DW, Guo P. Assessment and Comparison of Thermal Stability of Phosphorothioate-DNA, DNA, RNA, 2’-F RNA and LNA in the Context of Phi29 pRNA 3WJ. RNA. 2018 Jan; 24(1):67-76. [link][PDF]
  25. Jasinski DL, Yin H, Li Z, Guo P. The Hydrophobic Effect from Conjugated Chemicals or Drugs on in Vivo Biodistribution of RNA Nanoparticles. Hum Gene Ther. 2018 Jan;29(1):77-86. [link][PDF]

  26. 2017 
  27. Shi Z, Li SK, Charoenputtakun P, Liu C, Jasinski D, Guo P. RNA nanoparticle distribution and clearance in the eye after subconjunctival injection with and without thermosensitive hydrogels. J Control Release. 2017 Nov 21;270:14-22. [link][PDF]
  28. Guo S, Li H, Ma M, Fu J, Dong Y, Guo P. Size, Shape and Sequence-dependent Immunogenicity of RNA Nanoparticles. Mol Ther Nucleic Acids. 2017 Dec; 9:399-408. [link][PDF]
  29. Xu C, Haque F, Jasinski DL, Binzel DW, Shu D, Guo P. Favorable biodistribution, specific targeting and conditional endosomal escape of RNA nanoparticles in cancer therapy. Cancer Letters. 2017 Oct 5;414:57-70. [link][PDF]
  30. Haque F, Wang S, Wu T, Guo P. Advances in nanopore sensing promises to transform healthcare. Nanomedicine (Lond). 2017 Aug;12(16):1907-1909. [link][PDF]
  31. Haque F, Xu C, Jasinski DL, Li H, Guo P. Using Planar Phi29 pRNA Three-Way Junction to Control Size and Shape of RNA Nanoparticles for Biodistribution Profiling in Mice. Methods Mol Biol. 2017;1632:359-380. [link][PDF]
  32. Benkato K, O'Brien B, Bui MN, Jasinski DL, Guo P, Khisamutdinov EF. Evaluation of Thermal Stability of RNA Nanoparticles by Temperature Gradient Gel Electrophoresis (TGGE) in Native Condition. Methods Mol Biol. 2017;1632:123-133. [link][PDF]
  33. Xu Z, Sun Y, Weber JK, Cao Y, Wang W, Jasinski D, Guo P, Zhou R, Li J. Directional mechanical stability of Bacteriophage f29 motor's 3WJ-pRNA: Extraordinary robustness along portal axis. Sci Adv. 2017 May 26;3(5):e1601684. [link][PDF]
  34. Wang S, Zhou Z, Zhao Z, Zhang H, Haque F, Guo P. Channel of viral DNA packaging motor for real time kinetic analysis of peptide oxidation states. Biomaterials. 2017 Jan 30;126:10-17. [link][PDF]
  35. Yang X, Xu Y, Wang T, Shu D, Guo P, Miskimins K, Qian SY. Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells. Redox Biol. 2017 Jan 26;11:653-662. [link][PDF]
  36. Lee TJ, Yoo JY, Shu D, Li H, Zhang J, Yu JG, Jaime-Ramirez AC, Acunzo M, Romano G, Cui R, Sun HL, Luo Z, Old M, Kaur B, Guo P, Croce CM. RNA Nanoparticle-Based Targeted Therapy for Glioblastoma through Inhibition of Oncogenic miR-21. Mol Ther. 2017 Jul 5;25(7):1544-1555. [link][PDF]
  37. Jasinski D, Haque F, Binzel DW, Guo P. The Advancement of the Emerging Field of RNA Nanotechnology. ACS Nano. 2017 Feb 28;11(2):1142-1164. [link][PDF]
  38. Zhang Y, Leonard M, Shu Y, Yang Y, Shu D, Guo P, Zhang X. Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing using Multifunctional pRNA Nanoparticles. ACS Nano. 2017 Jan 24;11(1):335-346. [link][PDF]
  39. Pi F, Zhang H, Li H, Thiviyanathan V, Gorenstein DG, Sood AK, Guo P. RNA Nanoparticles Harboring Annexin A2 Aptamer Can Target Ovarian Cancer for Tumor-Specific Doxorubicin Delivery. Nanomedicine. 2017 Apr;13(3):1183-1193. [link][PDF]
  40. Zhao Z, Zhang H, Shu D, Montemagno C, Ding B, Li J, Guo P.  Construction of Asymmetrical Hexameric Biomimetic Motors with Continuous Single-Directional Motion by Sequential Coordination. Small. 2017 Jan;13(1). [link][PDF]
  41. Wang S, Ji Z, Yan E, Haque F, Guo P.  Three-step channel conformational changes common to DNA packaging motors of bacterial viruses T3, T4, SPP1, and Phi29.  Virology. 2017 Jan;500:285-291. [link][PDF]

  42. 2016 
  43. Khisamutdinov EF, Jasinski DL, Li H, Zhang K, Chiu W, Guo P. Fabrication of RNA 3D Nanoprisms for Loading and Protection of Small RNAs and Model Drugs.  Adv Mater. 2016 Dec;28(45):10079-10087. [link][PDF]
  44. Binzel DW, Khisamutdinov E, Vieweger M, Ortega J, Li J, Guo P.  Mechanism of three-component collision to produce ultrastable pRNA three-way junction of Phi29 DNA-packaging motor by kinetic assessment.  RNA.  2016 Nov;22(11):1710-1718. [link][PDF]
  45. Zhou Z, Ji Z, Wang S, Haque F, Guo P. Oriented single directional insertion of nanochannel of bacteriophage SPP1 DNA packaging motor into lipid bilayer via polar hydrophobicity. Biomaterials. 2016 Oct;105:222-7. [link][PDF]
  46. Zhao Z, De-Donatis GM, Schwartz C, Fang H, Li J, Guo P. An arginine finger regulates sequential action of asymmetrical hexameric ATPase in dsDNA translocation motor. Mol Cell Biol. 2016 Sep 12;36(19):2514-23. [link][PDF]
  47. Ji Z, Wang S, Zhao Z, Zhou Z, Haque F, Guo P. Fingerprinting of Peptides with a Large Channel of Bacteriophage Phi29 DNA Packaging Motor. Small. 2016 Sep;12(33):4572-8. [link][PDF]
  48. Pi F, Zhao Z, Chelikani V, Yoder K, Kvaratskhelia M, Guo P. Development of Potent Antiviral Drugs Inspired by Viral Hexameric DNA Packaging Motors with Revolving Mechanism. J Virol. 2016 Aug 26;90(18):8036-46. [link][PDF]
  49. Li H, Zhang K, Pi F, Guo S, Shlyakhtenko L, Chiu W, Shu D, Guo P. Controllable Self-Assembly of RNA Tetrahedrons with Precise Shape and Size for Cancer Targeting. Adv Mater. 2016 Sep;28(34):7501-7. [link][PDF]
  50. Binzel DW, Shu Y, Li H, Sun M, Zhang Q, Shu D, Guo B, Guo P. Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology. Mol Ther. 2016 Aug;24(7):1267-77. [link][PDF]  
  51. Guo P, Noji H, Yengo CM, Zhao Z, Grainge I. Biological Nanomotors with a Revolution, Linear, or Rotation Motion Mechanism. Microbiol Mol Biol Rev. 2016 Mar 1;80(1):161-86. [link][PDF]
  52. Sharma A, Haque F, Pi F, Shlyakhtenko LS, Guo P. Controllable Self-assembly of RNA Dendrimers. Nanomedicine. 2016 Apr;12(3):835-44. [link][PDF]
  53. Pi F, Vieweger M, Zhao Z, Wang S, Guo P. Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotors. Expert Opin Drug Deliv. 2016;13(1):23-36. [link][PDF]

  54. 2015 
  55. Li H, Lee T, Dziubla T, Pi F, Guo S, Xu J, Li C, Haque F, Liang X-J, Guo P. RNA as a Stable Polymer to Build Controllable and Defined Nanostructures for Material and Biomedical Applications. Nano Today. 2015 Oct;10(5):631-655. [link][PDF]
  56. Shu D, Li H, Shu Y, Xiong G, Carson WE, Haque F, Xu R, Guo P. Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology. ACS Nano. 2015 Oct 27;9(10):9731-40. [link][PDF]
  57. Lee T, Yagati AK, Pi F, Sharma A, Choi JW, Guo P. Construction of RNA-Quantum Dot Chimera for Nanoscale Resistive Biomemory Application. ACS Nano. 2015 Jul 28;9(7):6675-82. [link][PDF]
  58. Cui D, Zhang C, Liu B, Shu Y, Du T, Shu D, Wang K, Dai F, Liu Y, Li C, Pan F, Yang Y, Ni J, Li H, Brand-Saberi B, Guo P. Regression of Gastric Cancer by Systemic Injection of RNA Nanoparticles Carrying both Ligand and siRNA.Sci Rep. 2015 Jul 3;5:10726. [link][PDF]
  59. Li H, Rychahou PG, Cui Z, Pi F, Evers BM, Shu D, Guo P, Luo W. RNA Nanoparticles Derived from Three-Way Junction of Phi29 Motor pRNA Are Resistant to I-125 and Cs-131 Radiation. Nucleic Acid Ther. 2015 July 20;25(4):188-197. [link][PDF]
  60. Shu D, Pi F, Wang C, Zhang P, Guo P. New approach to develop ultra-high inhibitory drug using the power-function of the stoichiometry of the targeted nanomachine or biocomplex. Nanomedicine 2015 Jul;10(12):1881-97. [link][PDF]
  61. Haque F, Wang S, Stites C, Chen L, Wang C, Guo P. Single pore translocation of folded, double-stranded, and tetra-stranded DNA through channel of bacteriophage phi29 DNA packaging motor. Biomaterials 2015;53:744-52. [Link] [PDF]
  62. Lee TJ, Haque F, Shu D, Yoo J, Li H, Yokel R, Horbinski C, Kim T, Kim S, Kwon C, Nakano I, Kaur B, Guo P, Croce CM. RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model. Oncotarget. 2015 Jun 20;6(17):14766-76. [Link][PDF]
  63. Rychahou P, Haque F, Shu Y, Zaytseva Y, Weiss HL, Lee EY, Mustain W, Valentino J, Guo P, Evers BM. Delivery of RNA Nanoparticles into Colorectal Cancer Metastases Following Systemic Administration. ACS Nano. 2015 Feb 24;9(2):1108-16. [link] [PDF]
  64. Khisamutdinov EF, Bui MN, Jasinski D, Zhao Z, Cui Z, Guo P. Simple Method for Constructing RNA Triangle, Square, Pentagon by Tuning Interior RNA 3WJ Angle from 60° to 90° or 108°.Methods Mol Biol. 2015;1316:181-93. [link] [PDF]
  65. Lee TJ, Haque F, Vieweger M, Yoo JY, Kaur B, Guo P, Croce CM. Functional assays for specific targeting and delivery of RNA nanoparticles to brain tumor. Methods in Molecular Biology. 2015;1297:137-52. [link] [PDF]
  66. Rychahou P, Shu Y, Haque F, Hu J, Guo P, Evers BM. Methods and assays for specific targeting and delivery of RNA nanoparticles to cancer metastases. Methods in Molecular Biology 2015;1297:121-35. [link][PDF]
  67. Zhang H, Pi F, Shu D, Vieweger M, Guo P. Using RNA nanoparticles with thermostable motifs and fluorogenic modules for real-time detection of RNA folding and turnover in prokaryotic and eukaryotic cells. Methods in Molecular Biology 2015;1297:95-111. [link][PDF]
  68. Jasinski DL, Schwartz CT, Haque F, Guo P. Large scale purification of RNA nanoparticles by preparative ultracentrifugation. Methods in Molecular Biology 2015;1297:67-82. [link][PDF]
  69. Haque F, Guo P. Overview of methods in RNA nanotechnology: synthesis, purification, and characterization of RNA nanoparticles. Methods in Molecular Biology 2015;1297:1-19. [link][PDF]

  70. 2014 
  71. Khisamutdinov EF, Li H, Jasinski DL, Chen J, Fu J, Guo P. Enhancing immunomodulation on innate immunity by shape transition among RNA triangle, square and pentagon nanovehicles. Nucleic Acids Res. 2014 Nov 1;42(15):9996-10004. [link][PDF]
  72. Fang H, Zhang P, Huang LP, Zhao Z, Pi F, Montemagno C, Guo P. Binomial distribution for quantification of protein subunits in biological Nanoassemblines and functional nanomachines. Nanomedicine 2014 Oct;10(7):1433-40. [link][PDF]
  73. Guo P, Grainge I, Zhao Z, Vieweger M. Two classes of nucleic acid translocation motors: rotation and revolution without rotation. Cell Biosci. 2014 Sep 16;4(1):54. [link][PDF]
  74. De-Donatis GM, Zhao Z, Wang S, Huang LP, Schwartz C, Tsodikov OV, Zhang H, Haque F, Guo P. Finding of widespread viral and bacterial revolution dsDNA translocation motors distinct from rotation motors by channel chirality and size. Cell & Bioscience 2014;4:30. Highly Accessed [link][PDF]
  75. Guo P, Zhao Z, Haak J, Wang S, Wu D, Meng B, Weitao T. Common mechanisms of DNA translocation motors in bacteria and viruses using one-way revolution mechanism without rotation. Biotechnology Advances. 2014;32:853–872. [link] [PDF].
  76. Jasinski DL, Khisamutdinov EF, Lyubchenko YL, Guo P. Physicochemically Tunable Polyfunctionalized RNA Square Architecture with Fluorogenic and Ribozymatic Properties. ACS Nano. 2014 Aug 26;8(8):7620-9. [link][PDF]
  77. Binzel DW, Khisamutdinov EF, Guo P. Entropy-Driven One-Step Formation of Phi29 pRNA 3WJ from Three RNA Fragments. Biochemistry. 2014 Apr 15;53(14):2221-31. [link][PDF]
  78. Khisamutdinov EF, Jasinski DL, Guo P. RNA as a Boiling-Resistant Anionic Polymer Material To Build Robust Structures with Defined Shape and Stoichiometry. ACS Nano. 2014 May 27;8(5):4771-81. Honored as ACS Editors’ Choice [link][PDF]
  79. Zhang H, Guo P. Single molecule photobleaching (SMPB) technology for counting of RNA, DNA, protein and other molecules in nanoparticles and biological complexes by TIRF instrumentation. Methods. 2014 May 15;67(2):169-76. [link][PDF]
  80. Guo P. Biophysical Studies Reveal New Evidence for One-Way Revolution Mechanism of Bacteriophage phi29 DNA Packaging Motor. Biophysical Journal. 2014 May 6;106(9):1837-8. [link][PDF]
  81. Feng L, Li SK, Liu H, Liu CY, Lasance K, Haque F, Shu D, Guo P. Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection. Pharm Res. 2014 Apr;31(4):1046-58. [link][PDF]
  82. Shu Y, Pi F, Sharma A, Rajabi M, Haque F, Shu D, Leggas M, Evers BM, Guo P. Stable RNA nanoparticles as potential new generation drugs for cancer therapy. Adv Drug Deliv Rev. 2014 Feb;66C:74-89. [link][PDF]
  83. Shu D, Khisamutdinov E, Zhang L, Guo P. Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor. Nucleic Acids Res. 2014 Jan;42(2):e10. [link][PDF]

  84. 2013 
  85. Wang S, Haque F, Rychahou PG, Evers BM, Guo P. Engineered Nanopore of Phi29 DNA-Packaging Motor for Real-Time Detection of Single Colon Cancer Specific Antibody in Serum. ACS Nano. 2013 Nov 26;7(11):9814-22. [link][PDF]
  86. Guo P, Schwartz C, Haak J, Zhao Z. Discovery of a New Motion Mechanism of Biomotors Analogous to the Earth Revolving around the Sun without Rotation. Virology. 2013 Nov;446(1-2):133-43. [link][PDF].
  87. Schwartz C, De Donatis GM, Zhang H, Fang H, Guo P. Revolution rather than rotation of AAA+ hexameric phi29 nanomotor for viral dsDNA packaging without coiling. Virology. 2013 Aug 15;443(1):28-39. [link][PDF]
  88. Schwartz C, De Donatis GM, Fang H, Guo P. The ATPase of the phi29 DNA packaging motor is a member of the hexameric AAA+ superfamily. Virology. 2013 Aug 15;443(1):20-7. [link][PDF]
  89. Shu Y, Shu D, Haque F, Guo P. Fabrication of pRNA Nanoparticles to Deliver Therapeutic RNAs and Bioactive Compounds into Tumor Cells. Nature Protocols 2013;8:1635-1659. [link][PDF]
  90. Li M, Yang Y, He ZX, Zhou ZW, Yang T, Guo P, Zhang X, Zhou SF. MicroRNA-561 Promotes Acetaminophen-Induced Hepatotoxicity in Hepg2 Cells and Primary Human Hepatocytes through Down-Regulation of the Nuclear Receptor Co-Repressor Dosage-Sensitive Sex Reversal Adrenal Hypoplasia Congenital Critical Region on X Chromosome, Gene 1 (DAX-1). Drug Metab Dispos. 2013 Oct 8. [link][PDF]
  91. Qiu M, Khisamutdinov E, Zhao Z, Pan C, Choi J, Leontis N, Guo P. RNA nanotechnology for computer design and in vivo computation. Philos Trans A Math Phys Eng Sci. 2013 Sep 2;371(2000):20120310. [link][PDF]
  92. Leontis N, Sweeney B, Haque F, Guo P. Conference Scene: Advances in RNA nanotechnology promise to transform medicine. Nanomedicine 2013 July;8(7):1051-1054. [link][PDF]
  93. Zhang H, Endrizzi J, Shu Y, Haque F, Sauter C, Shlyakhtenko L, Lyubchenko Y, Guo P, Chi Y. Crystal Structure of 3WJ Core Revealing Divalent Ion-promoted Thermostability and Assembly of the Phi29 Hexameric Motor pRNA. RNA 2013 Sep;19(9):1226-37. [link][PDF]
  94. Schwartz C, Guo P. Ultrastable pRNA hexameric ring gearing hexameric phi29 DNA-packaging motor by revolving without rotating and coiling. Curr Opin Biotechnol. 2013 Aug;24(4):581-90. [link][PDF]
  95. Shu Y, Haque F, Shu D, Li W, Zhu Z, Kotb M, Lyubchenko Y, Guo P. Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs. RNA. 2013 Jun;19(6):767-77. [link][PDF]
  96. Yin JJ, Sharma S, Shumyak SP, Wang ZX, Zhou ZW, Zhang Y, Guo P, Li CZ, Kanwar JR, Yang T, Mohapatra SS, Liu W, Duan W, Wang JC, Li Q, Zhang X, Tan J, Jia L, Liang J, Wei MQ, Li X, Zhou SF. Synthesis and biological evaluation of novel folic acid receptor-targeted, β-cyclodextrin-based drug complexes for cancer treatment. PLoS One. 2013 May 2;8(5):e62289. [link][PDF]
  97. Zhao Z, Khisamutdinov E, Schwartz C, Guo P. Mechanism of One-Way Traffic of Hexameric Phi29 DNA Packaging Motor with Four Electropositive Relaying Layers Facilitating Antiparallel Revolution. ACS Nano 2013;7(5):4082-92. [link][PDF]
  98. Geng J, Wang S, Fang H, Guo P. Channel Size Conversion of Phi29 DNA-Packaging Nanomotor for Discrimination of Single- and Double-Stranded Nucleic Acids. ACS Nano 2013;7(4):3315-23. [link][PDF]
  99. Haque F, Li J, Wu H, Liang X, Guo P. Solid-state and biological nanopore for real-time sensing of single chemical and sequencing of DNA. Nano Today. 2013 Feb; 8(1): 56-74. [link][PDF]
  100. Haque F, Geng J, Montemagno C, Guo P. Incorporation of viral DNA packaging motor channel in lipid bilayers for real-time, single-molecule sensing of chemicals and double-stranded DNA. Nature Protocols. 2013;8:373–392. [link][PDF]

  101. 2012 
  102. Reif R, Haque F, Guo P. Fluorogenic RNA Nanoparticles for Monitoring RNA Folding and Degradation in Real Time in Living Cells. Nucleic Acid Ther. 2012 Dec;22(6):428-37. [link][PDF]
  103. Shim J, Geng J, Ahn C, Guo P. Formation of lipid bilayers inside microfluidic channel array for monitoring membrane-embedded nanopores of phi29 DNA packaging nanomotor. Biomed Microdevices. 2012 Oct;14(5):921-8. [link][PDF]
  104. Haque F, Shu D, Shu Y, Shlyakhtenko L, Rychahou P, Evers M, Guo P. Ultrastable synergistic tetravalent RNA nanoparticles for targeting to cancers. Nano Today. 2012 Aug;7(4):245-57. [link][PDF]
  105. Guo P, Haque F, Hallahan B, Reif R, Li H. Uniqueness, advantages, challenges, solutions, and perspectives in therapeutics applying RNA nanotechnology. Nucleic Acid Ther. 2012 Aug;22(4):226-45. [link] [PDF]
  106. Guo P. Rolling Circle Transcription of Tandem siRNA to Generate Spherulitic RNA Nanoparticles for Cell Entry. Mol Ther Nucleic Acids. 2012 August; 1(8):e36. [link][PDF]
  107. Zhang H, Schwartz C, De Donatis GM, Guo P. ‘‘Push Through One-Way Valve’’ Mechanism of Viral DNA Packaging. Advances in Virus Research. 2012;83: 415-465. [link][PDF]
  108. Haque F, Lunn J, Fang H, Smithrud D, Guo P. Real-time sensing and discrimination of single chemicals using the channel of phi29 DNA packaging nanomotor. ACS Nano. 2012 Apr 24;6(4):3251-61. [link][PDF]
  109. Fang H, Jing P, Haque F, Guo P. Role of channel lysines and the "push through a one-way valve" mechanism of the viral DNA packaging motor. Biophys J. 2012 Jan 4;102(1):127-35. [link][PDF]
  110. Schwartz C, Fang H, Huang L, Guo P. Sequential action of ATPase, ATP, ADP, Pi and dsDNA in procapsid-free system to enlighten mechanism in viral dsDNA packaging. Nucleic Acids Res. 2012;40(6): 2577-2586. [link][PDF]

  111. 2011 
  112. Shu D, Shu Y, Haque F, Abdelmawla S, Guo P. Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics. Nature Nanotechnology 2011;6(10):658-67. [link] [pdf]
  113. Geng J, Guo P. Membrane-embedded channel of bacteriophage phi29 DNA-packaging motor for single molecule sensing and nanomedicine. Chinese Bulletin of Life Sciences 2011;23(11):1114-29. [link] [pdf]
  114. Geng J, Fang H, Haque F, Zhang L, Guo P. Three reversible and controllable discrete steps of channel gating of a viral DNA packaging motor. Biomaterials 2011;32(32):8234-42. [link] [pdf]
  115. Shu Y, Cinier M, Shu D, Guo P. Assembly of Multifunctional Phi29 pRNA Nanoparticles for Specific Delivery of SiRNA and other Therapeutics to Targeted Cells. Methods 2011;54(2):204-14. [link] [pdf]
  116. Shukla GC, Haque F, Tor Y, Wilhelmsson LM, Toulmé JJ, Isambert H, Guo P, Rossi JJ, Tenenbaum SA, Shapiro BA. A boost for the emerging field of RNA nanotechnology. ACS Nano 2011;5(5):3405-18. [link] [pdf]
  117. Abdelmawla S, Guo S, Zhang L, Pulukuri SM, Patankar P, Conley P, Trebley J, Guo P, Li QX. Pharmacological Characterization of Chemically Synthesized Monomeric phi29 pRNA Nanoparticles for Systemic Delivery. Mol Ther. 2011;19(7):1312-22. [link] [pdf]
  118. Shu Y, Cinier M, Fox SR, Ben-Johnathan N, Guo P. Assembly of Therapeutic pRNA-siRNA Nanoparticles Using Bipartite Approach. Mol Ther 2011;19(7):1304-11. [link] [pdf]
  119. Laing BM, Guo P, Bergstrom DE. Optimized method for the synthesis and purification of adenosine - Folic acid conjugates for use as transcription initiators in the preparation of modified RNA. Methods. 2011;54(2):260-6. [link] [pdf]
  120. Zhou J, Shu Y, Guo P, Smith DD, Rossi JJ. Dual Functional RNA Nanoparticles Containing Phi29 Motor pRNA and Anti-gp120 Aptamer for Cell-type Specific Delivery and HIV-1 Inhibition. Methods 2011;54(2):284-94. [link] [pdf].
  121. Guo P. RNA Nanotechnology: methods for synthesis, conjugation, assembly and application of RNA nanoparticles. Methods 2011;54(2):201-3. [link] [pdf]
  122. Tarapore P, Shu Y, Guo P, Ho SM. Application of Phi29 Motor pRNA for Targeted Therapeutic Delivery of siRNA Silencing Metallothionein-IIA and Survivin in Ovarian Cancers. Mol Ther. 2011;19(2):386-394. [link][pdf]
  123. Liu J, Guo S, Cinier M, Shlyakhtenko L, Shu Y, Chen C, Shen G, Guo P. Fabrication of Stable and RNase- Resistant RNA Nanoparticles Active in Gearing the Nanomotors for Viral DNA Packaging. ACS Nano 2011;5(1): 237. [link] [pdf]

  124. 2010 
  125. Green DJ, Wang JC, Xiao F, Cai Y, Balhorn R, Guo P, Cheng RH. Self-Assembly of Heptameric Nanoparticles Derived from Tag-Functionalized Phi29 Connectors. ACS Nano. 2010;4(12):7651-7659. [link] [pdf]
  126. Shu D, Zhang H, Petrenko R, Meller J, Guo P. Dual-Channel Single-Molecule Fluorescence Resonance Energy Transfer to Establish Distance Parameters for RNA Nanoparticles. ACS Nano 2010;4 (11):6843-6853. [link] [pdf]
  127. Guo P. The emerging field of RNA nanotechnology. Nature Nanotechnology. 2010;5:833. [link] [pdf]
  128. Ma X, Wang D, Wu Y, Ho R, Jia L, Guo P, Hu L, Xing G, Zeng Y, Liang XJ. AIDS Treatment with Novel Anti-HIV Compounds Improved by Nanotechnology. The AAPS Journal 2010;12:272-278. [link][pdf]
  129. Jing P, Haque F, Shu D, Montemagno CD, Guo P. One-Way Traffic of a Viral Motor Channel for Double-Stranded DNA Translocation. Nano Lett 2010;10(9):3620.[link] [pdf]
  130. Xiao F, Demeler B, Guo P. Assembly Mechanism of the Sixty-Subunit Nanoparticles via Interaction of RNA with the Reengineered Protein Connector of phi29 DNA-Packaging Motor. ACS Nano 2010;4(6):3293-3301. [link][pdf]
  131. Jing P, Haque F, Vonderheide AP, Montemagno C, Guo P. Robust Properties of Membrane-Embedded Connector Channel of Bacterial Virus Phi29 DNA Packaging Motor. Mol. BioSyst. 2010;6:1844-1852. [link] [pdf]
  132. Zhang H, Shu D, Wang W, Guo P. Design and application of single fluorophore dual-view imaging system containing both the objective- and prism-type TIRF. Proc. of SPIE. 2010;7571:757107. [link][pdf]
  133. Guo P, Coban O, Snead NM, Trebley J, Hoeprich S, Guo S, Shu Y. Engineering RNA for targeted siRNA delivery and medical application. Adv Drug Deliv Rev. 2010;62(6):650-666.[link] [pdf]

  134. Before 2010 
  135. Wendell D, Jing P, Geng J, Subramaniam V, Lee TJ, Montemagno CD, Guo P. Translocation of double stranded DNA through membrane adapted phi29 motor protein nanopore. Nature Nanotechnology 2009;4(11):765-72. [link][pdf]
  136. Lee TJ, Zhang H, Chang C, Savran C, Guo P. Engineering of the fluorescent-energy-conversion arm of phi29 DNA packaging motor for single-molecule studies. Small. 2009;5(21):2453-9.[link][pdf].
  137. Xiao F, Cai Y, Wang JC, Green D, Cheng RH, Demeler B, Guo P. Adjustable Ellipsoid Nanoparticles Assembled from Re-engineered Connectors of the Bacteriophage Phi29 DNA Packaging Motor. ACS Nano. 2009 Aug 25;3(8):2163-70. [link][pdf]
  138. Lee T, Schwartz C, Guo P. Construction of Bacteriophage Phi29 DNA Packaging Motor and Its Applications in Nanotechnology and Therapy. Annals of Biomedical Engineering 2009;37:2064-2081.[link][pdf]
  139. Xiao F, Sun JC, Coban O, Schoen P, Che-Yen Wang J, Cheng RH, Guo P. Fabrication of Massive Sheets of Single Layer Patterned Arrays Using Lipid Directed Reengineered Phi29 Motor Dodecamer. ACS Nano 2009;3(1):100-107. [link] [pdf]
  140. Zhang H, Shu D, Browne M, Guo P. Construction of a laser combiner for dual fluorescent single molecule imaging of pRNA of phi29 DNA-packaging motor. Biomedical Microdevices, 2009;12:97-106. [link][pdf].
  141. Moon JM, Akin D, Xuan Y, Ye PD, Guo P, Bashir R. Capture and alignment of phi29 viral particles in sub-40 nanometer porous alumina membranes. Biomed Microdevices 2009;11:135-142. [link] [pdf]
  142. Zhang HM, Su Y, Guo S, Yuan J, Lim T, Liu J, Guo P, Yang D. Targeted delivery of anti-coxsackievirus siRNAs using ligand-conjugated packaging RNAs. Antiviral Res. 2009;83(3):307-316. [link] [pdf]
  143. Li L, Liu J, Diao Z, Shu D, Guo P, Shen G. Evaluation of specific delivery of chimeric phi29 pRNA/siRNA nanoparticles to multiple tumor cells. Molecular Biosystems 2009;5:1361-1368. [link] [pdf]
  144. Zhang H, Shu D, Browne M, Guo P. Approaches for stoichiometry and distance measurement within nanometer bio-complex by dual-channel single molecule imaging. Proc. of IEEE-NIH Life Science Systems and Applications Workshop 2009 (LISSA 2009):124-127. [link][pdf]
  145. Shu Y, Shu D, Diao Z, Shen G, Guo P. Fabrication of polyvalent therapeutic RNA nanoparticles for specific delivery of siRNA, ribozyme and drugs to targeted cells for cancer therapy. Proc. of IEEE-NIH Life Science Systems and Applications Workshop 2009 (LISSA 2009):9-12. [link][pdf]  
  146. Chang C-L, Zhang H, Shu D, Guo P, Savran C. Bright-field analysis of Φ29 DNA packaging motor using a magneto-mechanical system. Applied Physics Letters 2008;93:153902. [link] [pdf]
  147. Cai Y, Xiao F, Guo P. The effect of N- or C-terminal alterations of the connector of bacteriophage phi29 DNA packaging motor on procapsid assembly, pRNA binding, and DNA packaging. Nanomedicine 2008;4:8-18. [link] [pdf]
  148. Xiao F, Zhang H, Guo P. Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging. Nucleic Acids Res 2008;36(20):6620-6632. [link] [pdf]
  149. Lee TJ, Zhang H, Liang D, Guo P. Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor. Virology 2008;380:69-74 [link][pdf]
  150. Ko SH, Chen Y, Shu D, Guo P, Mao C. Reversible switching of pRNA activity on the DNA packaging motor of bacteriophage phi29. J Am Chem Soc. 2008;130(52):17684-7. [link] [pdf]
  151. Fang Y, Shu D, Xiao F, Guo P, Qin PZ. Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging. Biochem Biophys Res Commun. 2008:372(4);589-94. [link] [pdf]
  152. DiMauro AJ, Lin D, Guo S, Karr DB, Tanner JJ, Guo P. Crystallization of phi29 spindle-shaped nano-bar anti-receptor with glycosidase domain. J Nanoscience and Nanotechnology. 2007;7:2616-2622.[link][pdf]
  153. Guo P, and Lee T. Viral nanomotors for packaging of dsDNA and dsRNA. Molecular Microbiology 2007;64(4):886-903. [link][pdf]  
  154. Shu D, Zhang H, Jin J, Guo P. Counting of six pRNAs of phi29 DNA-packaging motor with customized single-molecule dual-view system. The EMBO Journal 2007;26:527-537. [link][pdf]
  155. Zhang H, Shu D, Huang F, Guo P. Instrumentation and metrology for single RNA counting in biological complexes or nanoparticles by a single molecule dual-view system. RNA 2007;13:1793-1802. [link][pdf]
  156. Moll D, Guo P. Grouping of Ferritin and Gold Nanoparticles Conjugated to pRNA of the Phage phi29 DNA-Packaging Motor. J Nanoscience and Nanotechnology 2007;7:3257-3267. [link][pdf]
  157. Liu H, Guo S, Roll R, Li J, Diao Z, Shao N, Riley MR, Cole AM, Robinson JP, Snead NM, Shen G, Guo P. Phi29 pRNA Vector for Efficient Escort of Hammerhead Ribozyme Targeting Survivin in Multiple Cancer Cells. Cancer Biol. Ther. 2007;6(5):697-704. [link] [pdf]
  158. Sun J, Cai Y, Moll D, Guo P.  Controlling bacteriophage phi29 DNA-packaging motor by addition or discharge of a peptide at N-terminus of connector protein that interacts with pRNA. Nucleic Acids Research. 2006;34(19):5482-90. [link] [pdf]
  159. Guo S, Huang F, Guo P. Construction of folate-conjugated phage phi29 motor pRNA for delivery of chimeric siRNA to nasopharyngeal carcinoma cells. Gene Ther. 2006;13:814-820. [link][pdf]
  160. Lee T, Guo P. Interaction of gp16 with pRNA and DNA for genome packaging by the motor of bacterial virus phi29.  J Mol Biol. 2006;356:589-599.[link][pdf]
  161. Khaled A, Guo S, Li F, Guo P. Controllable Self-Assembly of Nanoparticles for Specific Delivery of Multiple Therapeutic Molecules to Cancer Cells Using RNA Nanotechnology. Nano Letters 2005;5:1797-1808. [link] [pdf]
  162. Guo P. RNA Nanotechnology: Engineering, Assembly and Applications in Detection, Gene Delivery and Therapy. Journal of Nanoscience and Nanotechnology 2005;5(12):1964-1982.[http://docs.lib.purdue.edu/nanodocs/19]
  163. Guo P. A Special Issue on Bionanotechnology. Journal of Nanoscience and Nanotechnology 2005;5(12):i-iii.[http://docs.lib.purdue.edu/nanodocs/18]
  164. Guo P, Wei C. Quantum dots for robust and simple assays using single particles in nanodevices. Nanomedicine 2005;2:122-124.[link] [pdf]
  165. Guo P. Bacterial Virus phi29 DNA-Packaging Motor and Its Potential Applications in Gene Therapy and Nanotechnology. Methods Mol.Biol. 2005;300:285-324. [link] [pdf]
  166. Guo S, Tschammer N, Mohammed S, Guo P. Specific Delivery of Therapeutic RNAs to Cancer Cells via the Dimerization Mechanism of phi29 Motor pRNA. Human Gene Therapy. 2005;16(9):1097-1109S. [link] [pdf]
  167. Shu D, Moll W, Guo P. Construction of an Imitating Nanomotor Driven by Six ATP-binding RNAs of Bacterial Virus Phi29. in Electrochemical Society 2004 Proceedings - Nanoscale Devices, Materials, and Biological Systems: Fundamental and Applications, 2005. Vol.2004-13:639-652.
  168. Moll D, Guo P. Translocation of nicked but not gapped DNA by the packaging motor of bacteriophage phi29. J Mol Biol. 2005;351:100-107. [link][pdf]
  169. Hall J, Moll D, Zhang W,Guo P, Stonehouse N, Urquidi-Macdonald M. Determination of molecular size, distance, and stoichiometry of bionanoparticles using nanoscale measurement techniques. Handbook of Nanostructured Biomaterials and Their Applications in Nanobiotechnology, edited by H.S.Nalwa, American Scientific Publishers, Los Angeles 2005;1:477-493.
  170. Xiao F, Moll W, Guo S, Guo P. Binding of pRNA to the N-terminal fourteen-amino acids of connector protein of bacterialphage phi29. Nucleic Acids Research 2005;33(8):2640-9.[link][pdf]
  171. Guo Y, Blocker F, Guo P. Construction of connector arrays with tetragonal to decagonal transition induced by pRNA of phi29 DNA-packaging motor. J Nanoscience and Nanotechnology. 2005;5:856-863. [link][pdf]  
  172. Shu D, Moll D, Deng Z, Mao C, Guo P. Bottom-up assembly of RNA arrays and superstructures as potential parts in nanotechnology. Nano Letters 2004;4:1717-1724. [link][pdf]
  173. Shu D, Huang L, Guo P. A simple mathematical formula for stoichiometry quantification of viral and nanobiological assemblage using slopes of log/log plot curves. J Virol Methods 2004;115:19-30. [link][pdf]
  174. Grigoriev D, Moll D, Hall J, Guo P. Bionanomotors. ENN-Encyclopedia of Nanoscience and Nanotechnology. American Scientific Publishers, Stevenson Ranch. 2003;1:361-374.
  175. Shu D, Guo P.  A viral RNA that binds ATP and contains a motif similar to an ATP-binding aptamer from SELEX. J Biol Chem. 2003;278(9):7119-7125 [link][pdf]
  176. Hoeprich S, Qi G, Guo S, Shu D, Wang Y, Guo P. Bacterial virus phi29 pRNA as a Hammerhead Ribozyme Escort to Destroy Hepatitis B Virus, Gene Ther. 2003;10:1258-67. [link][pdf]
  177. Shu D, Huang L, Hoeprich S, Guo P. Construction of phi29 DNA-packaging RNA (pRNA) Monomers, Dimers and Trimers With Variable Sizes and Shapes as Potential Parts for Nano-devices.  Journal of Nanoscience and Nanotechnology 2003;3:1-8 [link][pdf]
  178. Guo S, Shu D, Simon M, Guo P. Gene cloning, purification and stoichiometry quantification of phi29 anti-receptor gp12 with potential use as special ligand for gene delivery. Gene 2003;315:145-52. [link][pdf]
  179. Huang L, Guo P. Use of acetone to attain highly active and soluble DNA packaging protein Gp16 of Phi29 for ATPase assay. Virology 2003 Aug 1;312(2):449-457. [link][pdf]
  180. Huang L, Guo P.  Use of PEG to acquire highly soluble DNA-packaging enzyme gp16 of bacterial virus phi29 for stoichiometry quantification.  J. J. Virol Meth. 2003;109:235-244. [link][pdf]
  181. Shu D, Guo P. Only one pRNA hexamer but multiple copies of the DNA-packaging protein gp16 are needed for the motor to package bacterial virus phi29 genomic DNA Virology 309 2002: 108-113. [link][pdf]
  182. Guo P. Structure and function of phi29 hexameric RNA that drives the viral DNA packaging motor. Progress in Nucleic Acids Research 2002;72:415-474. [pdf]
  183. Hoeprich S, Guo P. Computer Modeling of Three-dimensional Structure of DNA-packaging RNA (pRNA) Monomer, Dimer, and Hexamer of Phi29 DNA Packaging Motor. J Biol Chem. 2002 Jun 7;277(23):20794-803. [link][pdf]
  184. Guo P. Methods for Structural and Functional Analysis of pRNA in Bacterial Virus Phi29 DNA Packaging Motor. Acta Biochem Biophys Sin. 2002;43(5):533-543.[link]
  185. Mat-Arip Y, Garver K, Chen C, Sheng S, Shao Z, Guo P. Three-dimensional Interaction of Phi29 pRNA Dimer Probed by Chemical Modification Interference, Cryo-FM,and Cross-linking. J Biol Chem. 2001;276(35):32575-84. [link][pdf]
  186. Zhang C, Trottier M, Guo P.  Chemical modification patterns of  active and inactive as well as  procasid-bound and unbound DNA packaging RNA of bacterial virus phi29. Virology 2001;281:281-293. [link][pdf]
  187. Trottier M, Mat-Arp Y, Zhang C, Chen C, Sheng S, Shao Z, Guo P. Probing the structure of monomers and dimers of the bacterial virus phi29 hexamer RNA complex by chemical modification. RNA 2000;6(9):1257-1266. [link][pdf]
  188. Chen C, Sheng S, Shao Z, Guo P. A Dimer as a Building Block in Assembling RNA. J. Biol. Chem. 2000;275(23): 17510-17516. [link][pdf]
  189. Garver K,Guo P. Mapping the inter-pRNA interaction of phage phi29 pRNA by site-specific photoaffinity crosslinking. J. Biol. Chem. 2000;275(4):2817-2824 . [link][pdf]
  190. Mohammad T, Chen C, Guo P, Morrison H. Photoinduced cross-linking of RNA by cis-ph(phen)2Cl2+ and cis-ph(phen)(phi)l2+. Bioorganic and Medicinal Chemistry Letters 1999;9:1703-1708. [link][pdf]
  191. Aggarwal N,  HogenEsch H, Guo P, North A, Suckow M and Mittal S. Biodegradable Alginate Microspheres as a Delivery System for Naked DNA. Can J. Vet. Res. 1999;63:148-152.  [link] [pdf]
  192. Chen C, Zhang C, Guo P. Sequence requirement for hand-in-hand interaction to form hexameric RNA complex for phage phi29 DNA packaging. RNA 1999;5:805-818. [link][pdf]
  193. Guo P, Zhang C, Chen C, Garver K, Trottier M,  Chen C. Inter-RNA Interaction of phage phi29 pRNA to Form a Hexameric Complex for DNA Transportation. Mol. Cell 1998;2:149-155. Featured in Cell [link] [pdf]
  194. Trottier M, Garver K, Zhang C,  Guo P. DNA-packaging pRNA as target for complete inhibition of viral assembly  in vitro  and in vivo. Nucleic Acids Symposium Series. 1997;36:187-189.  
  195. Chen C, Trottier MC, Guo P.  New approaches to  stoichiometry determination and mechanism investigation on RNA involved in intermediate reactions. Nucleic Acid Symp Series. 1997;36:190-193.
  196. Chen C, Guo P. Sequential action of six DNA-packaging pRNA during phage phi29 genomic DNA translocation. J. Virology 1997;71:3864-3871. [link][pdf]
  197. Garver K, Guo P. Boundary of pRNA functional domains and minimum pRNA sequence requirement for specific connector binding and DNA packaging of phage phi29.  RNA 1997;3:1068-1079. [link][pdf]
  198. Chen C. Guo P.  Magnesium-induced conformational change of pRNA for procapsid recognition and binding during bacteriophage phi29 DNA packaging.  J. Virology 1997;71: 495-500. [link][pdf]
  199. Trottier M, Guo P.  Approaches to Determine Stoichiometry of Viral Assembly Components.  J. Virology 1997;71:487-494. [link][pdf]
  200. Zhang CL, Tellinghuiesn T, Guo P.  Use of circular permutation to assess six bulges and four loops of DNA-packaging pRNA of bacteriophage phi29. RNA 1997;3:315-322. [link][pdf]
  201. Huang, Q., Y. Mat-Arip, and P. Guo. Sequencing of a 5.5-kb DNA fragment and identification of a gene coding for a subunit of the helicase/primase complex of avian Laryngotracheitis virus (ILTV). Virus Gene 1997;15:(2):119-121. [link][pdf]
  202. Trottier M, Zhang CL, Guo P.  Complete inhibition of virion assembly in vivo  with mutant pRNA essential for phage phi29 DNA packaging. J Virol 1996;70:55-61. [pdf][pdf]
  203. Lee CS, Guo P.  Sequential interactions of structural proteins in phage phi29 procapsid assembly. J Virol 1995;69:5024-5032. [link][pdf]
  204. Lee CS, Guo P.  In vitro assembly of infectious virions of ds-DNA phage phi29 from cloned gene products and synthetic nucleic acids. J Virol 1995;69:5018-5023. [link] [pdf]
  205. Zhang CL, Tellinghuiesn T, Guo P.  Confirmation of the helical structure of the 5’/3’ termini of the essential DNA packaging pRNA of phage phi29. RNA 1995;1:1041-1050.  [link] [pdf]
  206. Zhang CL, Trottier M, Guo P.  Circularly permuted viral pRNA active and specific in the packaging of bacteriophage phi29 DNA. Virology 1995;207:442-451. [link][pdf]
  207. Zhang CL, Garver K, Guo P.  Inhibition of phage phi29 assembly by antisense oligonucleotides targeting viral pRNA essential for DNA packaging. Virology 1995;211:568-576.[pdf]
  208. Scholz, E, Guo P. Construction of Recombinant Avian Infectious Laryngotracheitis Virus with TK Gene disrupted by ß-gal Coding Sequence. In Imm Viral Inf. Proc. 3rd Intl Cong Vet. Virol 1995: 379-384.
  209. Guo, P, Scholz E, Maloney B, Welniak E.  Construction of recombinant avian infectious laryngotracheitis virus expressing the b-galactosidase gene and DNA sequencing of the insertion region. Virology 1994;202:771-781. [link][pdf]
  210. Lee C, Guo P.  A highly sensitive system for the assay of in vitro  viral assembly of bacteriophage phi29  of Bacillus subtilis. Virology 1994;202:1039-1042. [pdf]
  211. Scholz, E., Porter RE, Guo P.  Differential diagnosis of infectious laryngotracheitis from other avian respiratory disease by a simplified PCR procedure. J Virol Meth.  1994;50:313-322. [link] [pdf]
  212. Zhang, CL, Lee C-S, Guo P.  The proximate 5’ and 3’ ends of the 120-base viral RNA (pRNA) are crucial for the packaging of bacteriophage phi29 DNA. Virology 1994;201:77-85. [link] [pdf]
  213. Guo, P, Trottier M. Biological and biochemical properties of the small viral RNA (pRNA) essential for the packaging of the double-stranded DNA of phage phi29. Seminars in Virology 1994;5:27-37. [link]
  214. Guo, P. Editor’s Introduction: Principles, perspectives, and potential applications in viral assembly. Seminars in Virology 1994;5(1):1-3.
  215. Guo, P, Scholz E, Turek J, Nordgren R, Maloney B. Assembly pathway of avian infectious laryngotracheitis virus. Am J Vet Res 1993;54:2031-2039. [link]
  216. Scholz, E, Welniak E, Nyholm T, Guo P.  An avian hepatoma cell line for the cultivation of infectious laryngotracheitis virus and for the expression of foreign genes with a mammalian promoter. J Virol Meth 1993;43:273-286. [link] [pdf]
  217. Lee, C-S, Guo P.  Tracking and elimination of a interfering polypeptide co-expressed with the vaccinia virus mRNA Capping Enzyme. Protein Expression and Purification 1993;4:114-119. [link] [pdf]
  218. Guo, P, Erickson S, Xu W, Olson N, Baker TS, Anderson D.  Regulation of the phage phi29 prohead shape and size by the portal vertex. Virology 1991;183:366-373. [link][pdf]
  219. Guo, P, Rajogopal B, Anderson D, Erickson S, Lee C-S.  sRNA of bacteriophage phi29 of B.subtilis mediates DNA packaging of phi29 proheads assembled in E. coli. Virology 1991;185:395-400. [link] [pdf]
  220. Guo, P, Moss B.  Interaction and mutual stabilization of the two subunits of vaccinia virus mRNA capping enzyme co-expressed in Escherichia coli. Proc Natl Acad Sci USA 1990;87:4023-4027. [link] [pdf]
  221. Guo, P, Goebel S, Perkus M, Taylor J, Norton E, Allen G, Languet B, Desmettre P, Paoletti E.  Coexpression by vaccinia virus recombinants of equine herpesvirus 1 glycoproteins gp13 and 14 results in potentiated immunity. J Virol 1990;64:2399-2406. [link][pdf]
  222. Guo, P. Characterization of the gene and an antigenic determinant of equine herpesvirus 1 glycoprotein 14 with homology to gB-equivalent glycoprotein of other herpesvirus. Gene 1990;87:249-255. [link] [pdf]
  223. Guo, P, Goebel S, Davis S, Perkus M, Languet B, Desmettre P, Allen G, Paoletti E.  Expression of the equine herpesvirus type 1 gene encoding glycoprotein gp13 in recombinant vaccinia virus and protection of immunized animals. J Virol 1989;63:4189-4198. [link] [pdf]
  224. Guo, P. Mechanism of DNA packaging in ds-DNA bacteriophages. Virogica Sinica 1988;2:229-2
  225. Guo, P.  Inhibition of novobiocin, coumermycin A, oxolinic acid, nalidixic, ethidium bromide and ATP analogue on the packaging of phi29 DNA in vitro. Virologica Sinica 1988;2:198-205.
  226. Guo, P, Peterson C, Anderson D.  Prohead and DNA-gp3-dependent ATPase activity of the DNA packaging protein gp16 of bacteriophage phi29. J Mol Biol 1987;197:229-236. [pdf]
  227. Guo, P, Erickson S, Anderson D.  A small viral RNA is required for in vitro packaging of bacteriophage phi29 DNA. Science 1987;236:690-694. [link] [pdf]
  228. Guo, P, Bailey S, Bodley JW, Anderson D.  Characterization of the small RNA of the bacteriophage phi29 DNA packaging machine. Nucleic Acids Res. 1987;15:7081-7090. [link][pdf]
  229. Guo, P, Peterson C, Anderson D.  Initiation events in in vitro packaging of bacteriophage phi29 DNA-gp3. J Mol Biol 1987;197:219-228. [link] [pdf]
  230. Guo, P, Grimes S, Anderson D.  A defined system for in vitro packaging of DNA-gp3 of the Bacillus subtilis bacteriophage phi29. Proc Natl Acad Sci USA 1986;83:3505-3509. [link] [pdf]

[Pubmed] Publications in Pubmed after 2002

[Updated on 06/09/2016]