Program
Zoom link
4th Conference on Biomotors, Virus Assembly, and RNA Nanobiotechnology in 2023
Register here!
Agenda here!
Organizing Institutes: The Ohio State University
Center for RNA Nanobiotechnology and Nanomedicine
The Center for RNA Biology
International Society of RNA Nanotechnology & Nanomedicine (ISRNN)




Date: December 18th - December 20th, 2023;
Agenda: Download Here!
Location: Virtually on Zoom
MENU
We are pleased to announce the Fourth Conference on Biomotors, Virus Assembly, and RNA Nanobiotechnology to be held on Zoom (link will be available here soon). We have invited some of the leading scientists and engineers working in the diverse fields of chemistry, biochemistry, biophysics, structural biology, microbiology, cell biology, materials, and nanotechnology to participate.
Due to the great potential in the application of biomotors and viral components in nanotechnology, one motivation of organizing this conference is to promote the participation of more bioscientists into the field of nanobiotechnology. Our cross-disiplinary approach to virus assembly, biomotor, and nanobiotechnology research is designed to foster collaborations among scientists.
Conference Chair
Peixuan Guo
Fellow of the National Academy of Inventors
Sylvan Frank Endowed Chair in Pharmaceutics and Drug Delivery,
College of Pharmacy and College of Medicine
Comprehensive Cancer Center
Director of Center for RNA Nanobiotechnology and Nanomedicine,
The Ohio State University,
460 W. 12th Ave, BRT, Rm 406,
Columbus, OH 43210, USA
President of the International Society of
RNA Nanotechnology and Nanomedicine (ISRNN)
Personal Web Page: http://rnanano.osu.edu/Guo/peixuanguo.html
Assistant: Cheyenne Wagner wagner.1330@osu.edu, 614-293-2188
Co-chair
Sarah Woodson
T.C. Jenkins Professor;
Dept. of Biophysics;
Johns Hopkins University,
Baltimore, USA
Co-chair
Gino Cingolani
Professor;
Dept. of Biochemistry and
Molecular Genetics;
The University of Alabama
- Birmingham, USA
MENU
Due to the great potential in the application of biomotors and viral components in nanotechnology, one motivation of organizing this conference is to promote the participation of more bioscientists into the field of nanobiotechnology. Our cross-disiplinary approach to virus assembly, biomotor, and nanobiotechnology research is designed to foster collaborations among scientists.

Peixuan Guo
Fellow of the National Academy of Inventors
Sylvan Frank Endowed Chair in Pharmaceutics and Drug Delivery,
College of Pharmacy and College of Medicine
Comprehensive Cancer Center
Director of Center for RNA Nanobiotechnology and Nanomedicine,
The Ohio State University,
460 W. 12th Ave, BRT, Rm 406,
Columbus, OH 43210, USA
President of the International Society of
RNA Nanotechnology and Nanomedicine (ISRNN)
Personal Web Page: http://rnanano.osu.edu/Guo/peixuanguo.html
Assistant: Cheyenne Wagner wagner.1330@osu.edu, 614-293-2188

Sarah Woodson
T.C. Jenkins Professor;
Dept. of Biophysics;
Johns Hopkins University,
Baltimore, USA

Gino Cingolani
Professor;
Dept. of Biochemistry and
Molecular Genetics;
The University of Alabama
- Birmingham, USA

Speakers and Session Chairs (listed in first name alphabetical order)
Constantly Updating
Aijun Wang
Professor;
Engineering extracellular vesicles and lipid nanoparticles for targeted delivery (Theranostics 2022 & Bioact Mater. 2023);
University of California, Davis, USABrett VanVeller
Associate Professor;
New peptide bond isosteres provide more intuitive hydrogen-bonding rules (J. Am. Chem. Soc. 2022);
Iowa State University, USABruce Shapiro
NCI Scientist Emeritus;
Former Senior Investigator and Head of RNA Structure and Design Section;
A Brief History of My Time: The Path from RNA Structure Prediction and Analysis to RNA Nanobiology (Nano Lett. 2014 & Nanoscale 2020 & Molecular Therapy - Nucleic Acids. 2020);
NIH/NCI Center for Cancer Research, USACheemeng Tan
Associate Professor;
Designer Artificial Micro-Nano Devices: Fusing Synthetic Biology and Nanoengineering (Nature Communications 2020);
University of California, Davis, USAChunyan Wang
Associate Research Scientist;
Structural insights into inner core remodeling of bacteriophage T7 during infection initiation (Nature Microbiology 2019);
Yale University, USADaniel Binzel
Research Assistant Professor;
Controlled siRNA and miRNA delivery by exosomes to overcome drug resistance in cancers (ACS Nano 2019 & Nature Nanotech 2018);
The Ohio State University, USADavid Lilley
Professor & Fellow of Royal Society;
Expanding the chemical limits of RNA catalysis (Nat Chem Biol. 2017 & Cell Chem Biol. 2017);
University of Dundee, UK
Deepak Koirala
Assistant Professor;
Structural basis for RNA structure-mediated enteroviral genome replication (Nucleic Acids Res. 2018 & Nature Chemical Biology 2022);
University of Maryland, Baltimore County, USA
Dmitri Kudryashov
Professor;
Under the influence: reversal of the actin filament motor polarity by Vibrio VopF/VopL effectors(Nature Structural & Molecular Biology 2022);
The Ohio State University, USADorothy Hawkins
Postdoctoral Research Associate;
The HK97 Packaging Termination Assembly (Nature 2023 & Nucleic Acids Research 2023);
University of York, UKElisa Franco
Professor;
Building artificial RNA organelles via phase separation (Nature Chemistry 2019);
University of California at Los Angeles, USA-
Emil Khisamutdinov
Associate Professor;
Toehold-Mediated Shape Transition of Nucleic Acid Nanoparticles (Nanomaterials 2018 & ACS Appl. Mater. Interfaces 2023);
Ball State University, USA
-
Gino Cingolani
Professor;
Nuclear Import of Hepatitis B Virus (HBV) nucleocapsid (Nat Commun. 2017 & Biophysical J 2019);
The University of Alabama at Birmingham, USA -
Haichen Wu
Professor;
Nanopore-based protein sequencing (JACS 2011 & Anal Chem. 2016);
Institute of High Energy Physics, CAS, China
Haoyun Yang
On behalf of Dr. Mark Foster;
Senior Researcher;
Nearest-neighbor cooperativity in the Bacillus ring-shaped trp RNA binding attenuation protein (TRAP) from protein engineering and cryo-EM (PNAS 2017 & Biophysical Journal 2017);
The Ohio State University, USA-
Hirohide Saito
Professor;
Synthetic RNA and RNP technologies to manipulate cells (Nat Commun. 2017);
Kyoto University, Japan Hiroyuki Noji
Professor;
Molecular mechanism of Maxwell’s demon-like inhibitor, IF1 of mitochondrial ATP synthase (Science 2011, Nat. Commun. 2014 & Sci Rep. 2015);
University of Tokyo, JapanHolland Cheng
Professor;
Noninvasive PPM: cryoEM-guided design of a modular biocapsid for precision and personalized nanomedicine (Cell 1995 & Journal of Structural Biology 1996 & Nanomedicine 2016);
University of California, Davis, USA-
Hui Wei
Professor;
Nanozymes for translational medicine: several cases of studies (Nat. Commun. 2019 & Chem. Soc. Rev. 2019);
Nanjing University, China
-
Irina Artsimovitch
Professor;
Oligomerization as a stress response mechanism (Nucleic Acids Research 2022);
The Ohio State University, USA
-
Janusz Bujnicki
Professor, Member of Academia Europaea, Exec. Editor of Nucleic Acids Research;
RNA 3D structure and interactions (Nucleic Acids Res. 2016 & PLoS Comput Biol. 2021);
International Institute of Molecular and Cell Biology in Warsaw, Poland Jing Jin
On behalf of Dr. Wah Chiu;
Senior Scientist;
Structural insights into the modulation of coronavirus spike tilting and infectivity by hinge glycans (Nature Microbiology 2022);
Vitalant Institute - UCSF and Stanford University, USAJoanna Sztuba-Solinska
Principal Scientist;
Connecting the dots: how RNA biology dictates mRNA vaccine efficacy (Journal of Imaging 2022);
Pfizer Inc.Juan Luis Vivero-Escoto
Professor;
Multimodal Mesoporous Silica Nanoparticles for the Efficient Delivery of Nucleic Acids to Treat Cancer (Journal of Controlled Release 2022);
University of North Carolina – Charlotte, USAKai Jin
On behalf of Dr. Peixuan Guo;
Graduate Student;
RNA nanoparticles solubilize and targeted deliver hydrophobic SN38 for colorectal cancer treatment;
The Ohio State University, USA-
Karin Musier-Forsyth
Professor;
How a two-nucleotide difference in a 9.4 kilobase genome dictates HIV-1 viral RNA fate (J. Biol. Chem. 2018 & J. Virol. 2018);
The Ohio State University, USA
Kevin Li
Professor;
Ocular Delivery of Angiogenesis-inhibiting RNA Nanoparticles (Pharmaceutical Research 2023);
University of Cincinnati, USAKirill Afonin
Professor;
Locking and unlocking biological functions of extracellular proteins with immunoquiescent nucleic acid nanoparticles (Nano Letters 2018 & Nucl. Acids Res. 2017);
University of North Carolina – Charlotte, USA-
Li-Qun (Andrew) Gu
Professor;
RNA-small molecule interaction study in the nanopore (ACS Nano 2017 & Nat Commun. 2017 & PNAS 2023);
University of Missouri, USA
-
Madeline Sherlock
Scientist;
Viral RNA structures induce downstream reinitiation through dynamic ribosome interactions (RNA 2021 & Science 2021);
New York Structural Biology Center, USA
-
Margaret Bohmer
On behalf of Dr. Peixuan Guo;
Graduate Student;
Confirmation of a Hexameric Stoichiometry of Motor pRNA Using a Chimeric pRNA Derived From Two Bacteriophages (iScience 2022);
The Ohio State University, USA
-
Michelle Scott
Professor;
How do specific small nucleolar RNAs promote cancer proliferation and survival? (Nucleic Acids Research 2023);
Université de Sherbrooke, Canada
-
Morgan Chandler
Scientist;
3D Model Systems for Developing Therapeutic Nucleic Acids (Small 2022);
MIMETAS Inc.
-
Nikolay Dokholyan
Professor;
NanoComputing Agents: Hacking Cellular Behavior (Science Advances 2023);
Penn State, USA
Nils Walter
Professor;
A nascent riboswitch helix acts as fulcrum to integrate ligand, template, polymerase and cofactor signals for robust transcription regulation (Nature Communications 2022 & Nature Structural & Molecular Biology 2023 & Nature Reviews Nephrology 2023);
University of Michigan, USA-
Peixuan Guo
Professor & Director of Center for RNA Nanobiotechnology and Nanomedicine;
Phi29 DNA packaging motor and RNA nanotechnology (Nat Nano
technol. 2010, Nat Nanotechnol. 2011 & Nat Nanotechnol. 2018);
The Ohio State University, USA Rajgopal Govindarajan
Professor;
Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice (Nat Comm. 2019 & Nat Comm. 2021 & Nat Comm. 2023);
The Ohio State University, USA-
Renata de Freitas Saito
Researcher;
Anticoagulant RNA-DNA biomolecular platform for the management of cancer-associated thrombosis (Nanomedicine 2021);
University of Sao Paulo, Brazil
Richard Lease
Research Scientist;
Optimized nucleic acid structured-antisense fingerloop probes for improved target-mismatch discrimination, increased antisense length, and selectivity (ACS Synth. Biol. 2017);
The Ohio State University, USA-
Robert Batey
Professor;
Flipping the script: understanding riboswitch regulatory mechanisms from the perspective of their expression platform (ACS Chem. Biol. 2023);
University of Colorado, Boulder, USA
-
Robin Stanley
Senior Investigator;
SARS-CoV-2 Nsp15 Can’t Take Its Eyes off U (Structure 2017 & RNA 2018);
National Institute of Environmental Health Sciences, USA -
Sarah Woodson
Professor;
Co-transcriptional assembly of RNA (PNAS 2014 & PNAS 2016);
Johns Hopkins University, USA Shi-Jie Chen
Professor;
An Enhanced Knowledge-Based Approach for Screening RNA-Targeted Drugs (RNA 2017 & PNAS 2016 );
University of Missouri, USAShuo Huang
Professor;
Multi-scale Nanopore Analysis (Nature Nanotechnology 2022 & Nature Methods 2023 );
Nanjing University, China
-
Tae Jin Lee
Assistant Professor;
Extracellular vesicle based Targeted modulation of tumor suppressive miRNAs in glioblastoma (Mol Ther. 2017);
University of Texas Health Science Center at Houston, USA
Tianmin Fu
Assistant Professor;
Molecular mechanisms of Holliday junction branch migration catalyzed by an asymmetric RuvB hexamer (Nature 2023);
The Ohio State University, USAWalter Zahurancik
On behalf of Dr. Venkat Gopalan;
Postdoctoral Researcher;
Modulation of Archaeal Ribonuclease P Ribozyme Activity by Temperature- and Metal-ion–dependent Phase Separation (Methods in Enzymology 2021);
The Ohio State University, USAWayne Miles
Associate Professor;
Conversion of Chemical Antagonists into Small Cell Lung Cancer Ligands for RNA Nanoparticle Delivery (Nucleic Acids Research 2022);
The Ohio State University, USAXiaoming (Shawn) He
Professor;
Cold Responsive Nanotechnology-Potentiated Cryoimmunotherapy for Combating Cancer Metastasis (Nat Nanotechnol. 2019 & Nat Commun. 2023);
University of Maryland, USA-
Xiaoting Zhang
Professor;
Overcoming Breast Cancer Therapeutic Resistance by RNA Nanotherapeutics (ACS Nano 2017 & Cancer Res. 2018);
University of Cincinnati, USA
-
Ya-ming Hou
Professor;
Reading RNA modifications by an RNA-dependent RNA polymerase (Nucleic Acids Res. 2018 & RNA 2018);
Thomas Jefferson University, USA Yan Zhao
Professor;
Molecularly Imprinted Nanoparticles (MINPs) as Highly Selective Artificial Receptors and Enzymes (ACS Nano 2023);
Iowa State University, USAYi-Tao Long
Professor;
Nanopore and Nanoelectrochemical Biosensors (Nature Chemistry 2023 & Nature Nanotechnology 2022);
Nanjing University, ChinaYoudong Mao
Professor;
Watching molecular machines in action by AI-enhanced 4D cryo-EM (Nature 2019 & Mol. Cell 2017);
Peking University, ChinaYuanpei Li
Professor;
One-component new-chemical-entity nanomedicine for cancer treatment (Nature Nanotechnology 2020);
University of California, Davis, USA